Lipid Profile and Serum Uric Acid in Preeclampsia

Tushar Bansode, Satpute S, Jagtap A

Aim: To identify biochemical markers i. e. Lipid profile and serum uric acid for early diagnosis of preeclampsia. Material and Method: Study consisting of Group A-55 Non-pregnant normotensive normal women, Group B-55 women having normal uncomplicated pregnancy without Hypertension and Group C-55 women with preeclampsia. Fasting venous blood samples were collected during ante partum period and serum levels of Triglycerides (TG), Total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), high density lipoprotein cholesterol (HDL-C) and Uric Acid were measured. Result: Serum Total Cholesterol is significantly increased (p < 0.001) in group-C (208.34+/-24.88) as compared to group-B (176.4+/-12.07), Serum Triglycerides are significantly increased (p < 0.001) in group-C (158.27+/-21.98) as compared to group-B (129.84+/-11.32), Serum HDL levels are significantly decreased (p < 0.001) in group-C (28.6+/-4.80) as compared to group-B, 41.72+/-6.89), Serum LDL levels are significantly increased (p < 0.001) in group-C (137.10+/-13.75) as compared to group-B, (117.05+/-11.21 ),Serum VLDL levels are significantly increased (p < 0.001) in group-C (31.4+/-4.57) as compared to group-B (25.79+/-2.41), Serum Uric acid levels are significantly increased (p < 0.001) in group-C (7.44+/-0.81)as compared to group-B (4.08+/-0.93).Conclusion: The present study is consistent with previous studies suggesting that Plasma lipids appear to be of immense value in understanding the pathogenesis of preeclampsia .

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